Thermo Fisher Scientific UBA52 Monoclonal Antibody (OTI3C4), TrueMAB
Thermo Fisher Scientific의 UBA52 단클론 항체(OTI3C4)는 인간 UBA52 단백질을 인식하는 Mouse IgG1 항체로, Western blot에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 77–128 of human UBA52 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Ubiquitin is a highly conserved protein involved in targeting cellular proteins for degradation by the 26S proteasome. The UBA52 gene encodes a fusion protein consisting of ubiquitin at the N-terminus and ribosomal protein S27a at the C-terminus.
When expressed, it is processed into free ubiquitin monomers and ribosomal protein S27a, a component of the 40S ribosomal subunit. S27a contains C4-type zinc finger domains and is located in the cytoplasm.
Pseudogenes derived from this gene exist in the genome. Similarly, ribosomal proteins L40 and S30 are synthesized as fusion proteins with ubiquitin or ubiquitin-like proteins.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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