Thermo Fisher Scientific LPIN3 Monoclonal Antibody (OTI1F8), TrueMAB
LPIN3 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI1F8). Western blot에 최적화되어 있으며, Human 시료에 반응. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F8 |
| Immunogen | Full length human recombinant protein of human LPIN3 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Human lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice with mutations in the fatty liver dystrophy gene show similar phenotypes. The responsible mouse gene, Lpin1, encodes the nuclear protein lipin, which is highly expressed in adipose tissue and induced during preadipocyte differentiation.
Human homologs include LPIN1, LPIN2, and LPIN3, mapped to chromosomes 2p25, 18p11, and 20q11-q12, respectively. Mouse genes Lpin1, Lpin2, and Lpin3 are located on chromosomes 12, 17, and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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