Thermo Fisher Scientific ZNF451 Polyclonal Antibody
ZNF451 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB 및 IP에 사용 가능. 인간 ZNF451의 1011–1061번 잔기 영역을 면역원으로 제작. 1 mg/mL 농도의 액상 제품이며 4°C에서 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- A305177Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific ZNF451 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1011 to 1061 of Human Zinc finger protein 451 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
E3 SUMO-protein ligase; has a preference for SUMO2 and SUMO3 and facilitates UBE2I/UBC9-mediated sumoylation of target proteins (PubMed:26524493, PubMed:26524494).
Plays a role in protein SUMO2 modification in response to stress caused by DNA damage and by proteasome inhibitors (in vitro).
Required for MCM4 sumoylation. Has no activity with SUMO1 (PubMed:26524493).
Preferentially transfers an additional SUMO2 chain onto the SUMO2 consensus site Lys-11 (PubMed:26524493).
Negatively regulates transcriptional activation mediated by the SMAD4 complex in response to TGF-beta signaling.
Inhibits EP300-mediated acetylation of histone H3 at Lys-9 (PubMed:24324267).
Plays a role in regulating the transcription of AR targets (PubMed:18656483). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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