Thermo Fisher Scientific IGF2 Recombinant Rabbit Monoclonal Antibody (HL2132)
인간 IGF2 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합. HEK293 세포에서 발현되며 Protein A로 정제됨. 1 mg/mL 농도의 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2132 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminal region of human IGF2 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3092869 |
Product Specific Information
MA5-50393 has successfully been used in Indirect ELISA.
Target Information
The insulin-like growth factors (IGFs) are mitogenic polypeptide growth factors that stimulate proliferation and survival of various cell types, including muscle, bone, and cartilage tissue in vitro. IGFs are mainly produced by the liver but also by other tissues at specific times. They belong to the insulin gene family, which includes insulin and relaxin. IGFs share structural and functional similarity with insulin but exhibit higher growth-promoting activity. IGF-II expression is influenced by placental lactogen, while IGF-I expression is regulated by growth hormone. Both IGF-I and IGF-II signal through the tyrosine kinase type I receptor (IGF-IR), and IGF-II can also signal through the IGF-II/Mannose-6-phosphate receptor. Mature IGFs are generated by proteolytic processing of inactive precursor proteins containing N-terminal and C-terminal propeptide regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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