
Thermo Fisher Scientific Pepsinogen I Recombinant Rabbit Monoclonal Antibody (HL2137)
Pepsinogen I 단백질을 인식하는 recombinant rabbit monoclonal antibody (Clone HL2137). Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 시료에 반응. Protein A 정제, PBS buffer, 보존제 없음.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:3000 | |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent | |
| Immunocytochemistry (ICC/IF) | Assay-dependent | |
| ELISA | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | HL2137 |
| Immunogen | Recombinant fragment of human Pepsinogen I |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093703 |
Product Specific Information
MA5-50395 has successfully been used in Indirect ELISA.
Target Information
Gene/Protein: PGA5 (Pepsinogen 5, group I / Pepsinogen A)
Pepsinogens are inactive precursors of pepsin, the major acid protease in the stomach. Pepsin arises from pepsinogen by removal of a 41-amino-acid segment from the N-terminus. It is synthesized in the stomach lining, and hydrochloric acid is required for activation and maintenance of optimal acidity (pH 1–3). Pepsin cleaves peptide bonds involving aromatic amino acids, showing broad specificity. PGA5 belongs to the A1 subfamily of the pepsin family and is the predominant endopeptidase in vertebrate gastric juice. It is inhibited by ovUS-1, a uterine serpin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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