Thermo Fisher Scientific APEH/AARE Polyclonal Antibody
Rabbit polyclonal antibody targeting human APEH/AARE. Validated for Western blot and immunoprecipitation. Recognizes region 150–200 of human APEH. Supplied as liquid, 1 mg/mL, stored at 4 °C. Predicted to cross-react with rat and bovine.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 to 200 of human Acylamino-acid-releasing enzyme (APEH) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Bovine
Target Information
APEH (acylpeptide hydrolase) catalyzes the hydrolysis of terminal acetylated amino acids from small acetylated peptides. The resulting acetyl amino acid is further processed to acetate and a free amino acid by aminoacylase.
The APEH gene is located on chromosome 3 (3p21), near the aminoacylase gene. Deletions in this region are associated with reduced aminoacylase activity.
APEH is a homotetrameric protein (~300 kDa), with each subunit containing 732 amino acids. It plays a key role in removing oxidatively damaged proteins in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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