Thermo Fisher Scientific SARS-CoV-2 ORF3a (aa126-275), His Tag Recombinant Protein
SARS-CoV-2 ORF3a 단백질(aa126-275) His Tag 재조합 단백질로, E. coli에서 발현된 고순도(>95%) 연구용 시약입니다. Western blot, ELISA, Control 실험에 사용 가능하며, 바이러스 단백질 기능 연구에 적합합니다. PBS(pH 7.4) 용액 상태로 제공됩니다.
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Applications
- Western Blot (WB): Assay-dependent
- ELISA (ELISA): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Virus |
| Expression System | E. coli |
| Amino Acid Sequence | SARS-CoV-2 ORF3a, amino acids 126-275 |
| Molecular Weight | 22 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95% by reducing SDS-PAGE |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
ORF3A forms homotetrameric potassium-sensitive ion channels (viroporin) and may modulate virus release.
Up-regulates expression of fibrinogen subunits FGA, FGB, and FGG in host lung epithelial cells.
Induces apoptosis in cell culture.
Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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