Thermo Fisher Scientific N2DL4 Monoclonal Antibody (709116)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

8-25 µg/mL

-

Flow Cytometry (Flow)

0.25 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

709116

Immunogen

Mouse myeloma cell line NS0-derived recombinant human ULBP-4/RAET1E Gly30-Asp225 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:N2DL4,uniProtId:Q8TD07-1,ncbiNodeId:9606,antigenRange:30-225,antigenLength:263,antigenImageFileName:MA5-24328_N2DL4_Q8TD07-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24328_N2DL4_Q8TD07-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2606442

Product Specific Information

In Western blots, approximately 20% cross-reactivity with recombinant human (rh) ULBP-2 is observed and no cross-reactivity with rhULBP-1 or rhULBP-3 is observed.

Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.

Target Information

This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.