Thermo Fisher Scientific CAD Polyclonal Antibody
Thermo Fisher Scientific의 CAD Polyclonal Antibody는 인간 CAD 단백질을 인식하는 토끼 유래 IgG 항체로, IHC 및 IHC(P) 실험에 적합합니다. 액상 형태이며 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1650 and 1700 of human carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with: Mouse, Rat, Dog, Rabbit, Guinea pig, Pig, Orangutan, Monkey, Gorilla, Chimpanzee, Black rat, and Gray short-tailed opossum
Target Information
The de novo synthesis of pyrimidine nucleotides is essential for mammalian cell proliferation. The CAD gene encodes a trifunctional protein associated with the enzymatic activities of the first three enzymes in the six-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, linking MAPK activation to pyrimidine nucleotide biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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