Thermo Fisher Scientific Coagulation Factor VII/F7 Monoclonal Antibody (F7/3618)
인간 Coagulation Factor VII(F7)을 인식하는 단일클론 항체로, IHC, ELISA 등 다양한 분석에 사용 가능. Mouse IgG2b, kappa 아이소타입이며, 단백질 A/G로 정제된 액상 형태. PBS(pH 7.4) buffer에 보존제 없이 제공되며, -20°C에서 보관.
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- 2155-MSM8-P1ABX
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F7/3618 |
| Immunogen | Recombinant fragment (around aa 366–466) of human F7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by factor IXa, factor Xa, factor XIIa, or thrombin through minor proteolysis. Upon activation, factor VII forms a heavy chain containing a catalytic domain and a light chain containing two EGF-like domains, held together by a disulfide bond. In the presence of factor III and calcium ions, activated factor VII further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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