Thermo Fisher Scientific Coagulation Factor VII/F7 Monoclonal Antibody (F7/3618)
인간 Coagulation Factor VII를 인식하는 마우스 단클론 항체로, IHC, ELISA, Peptide Array 등에 사용 가능. 비결합형 액상 형태로 제공되며 Protein A/G로 정제됨. 4°C 보관, 동결 금지. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| ELISA | Assay-dependent |
| Peptide Array | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F7/3618 |
| Immunogen | Recombinant fragment (around aa 366–466) of human F7 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin through minor proteolysis. Upon activation, a heavy chain containing a catalytic domain and a light chain containing two EGF-like domains are generated, held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor further activates the coagulation cascade by converting factor IX to IXa and/or factor X to Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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