Thermo Fisher Scientific POLD1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human POLD1 catalytic subunit. Suitable for WB, IHC, and ICC/IF applications. Recognizes amino acids 808–1107 of POLD1. Provided in liquid form at 0.76 mg/mL, stored at -20°C.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 808–1107 of human POLD1 (NP_002682.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855605 |
Product Specific Information
Sequence of this protein is as follows:
RYAGLLFSSR PDAHDRMDCK GLEAVRRDNC PLVANLVTAS LRRLLIDRDP EGAVAHAQDV ISDLLCNRID ISQLVITKEL TRAASDYAGK QAHVELAERM RKRDPGSAPS LGDRVPYVII SAAKGVAAYM KSEDPLFVLE HSLPIDTQYY LEQQLAKPLL RIFEPILGEG RAEAVLLRGD HTRCKTVLTG KVGGLLAFAK RRNCCIGCRT VLSHQGAVCE FCQPRESELY QKEVSHLNAL EERFSRLWTQ CQRCQGSLHE DVICTSRDCP IFYMRKKVRK DLEDQEQLLR RFGPPGPEAW
Target Information
This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3′ to 5′ exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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