Thermo Fisher Scientific CEA (CEACAM5) Monoclonal Antibody (OTI1C2), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150

Product Specifications

Additional Formats

• Biotin
• Request custom conjugation

Product Specific Information

For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

CEA (Carcino Embryonic Antigen, CD66e) is synthesized during fetal development and re-expressed in intestinal carcinomas and other tumors.
It belongs to the immunoglobulin supergene family and functions as a cell adhesion molecule.
CEA antibodies are useful for identifying the origin of metastatic adenocarcinomas and distinguishing pulmonary adenocarcinomas from pleural mesotheliomas.
CEA family members are located on chromosome 19, and multiple pseudogenes are present within the same cluster.
The encoded protein mediates cell adhesion and participates in tissue organization, angiogenesis, apoptosis, tumor suppression, metastasis, and immune response modulation.
Multiple transcript variants exist, though not all full-length forms have been defined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.