Thermo Fisher Scientific Phospho-PDGFRA/PDGFRB (Tyr572, Tyr574) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

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Immunohistochemistry (IHC)

-

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Immunocytochemistry (ICC/IF)

1:100-1:500

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Product Specifications

Species Reactivity

Human, Mouse

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human PDGFRA that contains tyrosines 572 and 574 and PDGFRB tyrosines 579 and 581. The sequence is conserved in PDGFRA mouse, rat and frog. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDGFRA/PDGFRB,uniProtId:P09619-1,ncbiNodeId:9606,antigenRange:579|581,antigenLength:1106,antigenImageFileName:44-1000G_PDGFRAPDGFRB_P09619-1_Rabbit.svg,antigenImageFileNamePDP:44-1000G_PDGFRAPDGFRB_P09619-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:PDGFRA/PDGFRB,uniProtId:P16234-1,ncbiNodeId:9606,antigenRange:572|574,antigenLength:1089,antigenImageFileName:44-1000G_PDGFRAPDGFRB_P16234-1_Rabbit.svg,antigenImageFileNamePDP:44-1000G_PDGFRAPDGFRB_P16234-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

Dulbecco`s PBS, pH 7.3, with 1mg/mL BSA

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533550

Target Information

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.