Thermo Fisher Scientific HSPB8 Monoclonal Antibody (5G3)
인간 HSPB8 단백질을 인식하는 Mouse IgG3 단일클론 항체로 Western Blot과 ELISA에 사용 가능. 친화 크로마토그래피로 정제된 액상 형태이며, 보존제가 없는 PBS 용액에 저장. -20°C에서 보관하며 반복 동결·해동을 피해야 함.
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Applications
- Western Blot (WB): 1–5 µg/mL
- ELISA: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG3, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5G3 |
| Immunogen | HSPB8 (NP_055180, 97–196 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KVCVNVHSFK PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA SLSPEGLLII EAPQVPPYST FGESSFNNEL PQDSQEVTCT
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal region. Expression is induced by estrogen in estrogen receptor-positive breast cancer cells and functions as a chaperone in association with Bag3, a stimulator of macroautophagy. This gene is involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations are associated with neuromuscular diseases including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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