Thermo Fisher Scientific HSPB8 Monoclonal Antibody (5B12)
HSPB8 단백질을 인식하는 Mouse 모노클로날 항체로 Western blot 및 ELISA에 적합합니다. 인간 시료에 반응하며, 비결합형 액상 형태로 제공됩니다. 세포 증식, 자가포식 및 신경근 질환 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5B12 |
| Immunogen | HSPB8 (NP_055180, 97 a.a. ~196 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
KVCVNVHSFK PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA SLSPEGLLII EAPQVPPYST FGESSFNNEL PQDSQEVTCT
Target Information
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conserved alpha-crystallin domain at the C-terminal region. Expression of this gene is induced by estrogen in estrogen receptor-positive breast cancer cells. It functions as a chaperone in association with Bag3, a stimulator of macroautophagy. This gene is involved in regulation of cell proliferation, apoptosis, and carcinogenesis. Mutations in this gene are associated with neuromuscular diseases, including Charcot-Marie-Tooth disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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