Thermo Fisher Scientific MEF2C Monoclonal Antibody (6H2G2)
MEF2C 단백질을 검출하는 Mouse Monoclonal Antibody로, WB, IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합. Human 및 Mouse 시료에서 반응하며, 고순도의 Protein G 정제 항체. 장기 보관 시 -20°C에서 안정적 유지.
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Thermo Fisher Scientific MEF2C Monoclonal Antibody (6H2G2)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | – |
| Flow Cytometry (Flow) | 1:200–1:400 | – |
| ELISA | 1:10,000 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H2G2 |
| Immunogen | Purified recombinant fragment of human MEF2C (amino acids: 1–125) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538590 |
Product Specific Information
MA5-17119 targets MEF2C in indirect ELISA, FACS, IHC, and WB applications, showing reactivity with Human and Mouse samples.
The immunogen is a purified recombinant fragment of human MEF2C (amino acids 1–125) expressed in E. coli.
MA5-17119 detects MEF2C with a predicted molecular weight of approximately 51.2 kDa.
Target Information
MEF2C is a transcription activator that binds to the MEF2 element found in regulatory regions of many muscle-specific genes.
It controls cardiac morphogenesis and myogenesis, and is involved in vascular development.
MEF2C plays an essential role in hippocampal-dependent learning and memory by regulating excitatory synapses and synaptic transmission.
It is crucial for neuronal development, megakaryocyte and platelet formation, and B-cell survival and proliferation.
Also involved in neurogenesis and cortical architecture development. Isoforms 3 and 4, lacking the repressor domain, are more active than isoforms 1 and 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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