Thermo Fisher Scientific TMEM27 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1–10 µg/mL

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 5–15 µg/mL

Product Specifications

Product Specific Information

• In direct ELISAs, approximately 40% cross-reactivity with recombinant human Collectrin is observed.
• Reconstitute at 0.2 mg/mL in sterile PBS.

Target Information

TMEM27 (Transmembrane protein 27), also known as Collectrin, belongs to the TMEM27 family. It stimulates beta cell replication and acts as a membrane protein cleaved and shed by pancreatic beta cells, proposed as a biomarker for beta cell mass.
Western blot analysis of mouse collecting duct cell lines detected TMEM27 at an apparent molecular mass of 32 kDa.
TMEM27 is an N-glycosylated protein and forms dimers, with molecular weights of 64–75 kDa.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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