Thermo Fisher Scientific PSMD11 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Zebrafish, X. tropicalis, and Bovine

Target Information

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex composed of a 20S core and a 19S regulator.

• 20S core: 4 rings of 28 non-identical subunits (two rings of 7 alpha subunits, two rings of 7 beta subunits)
• 19S regulator: Consists of a base (6 ATPase and 2 non-ATPase subunits) and a lid (up to 10 non-ATPase subunits)
  Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
  The immunoproteasome processes class I MHC peptides. PSMD11 is a non-ATPase subunit of the 19S regulator.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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