Thermo Fisher Scientific PSMD11 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, D. melanogaster, Zebrafish, X. tropicalis, and Bovine

Target Information

The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.

• The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
• The 19S regulator includes a base (six ATPase subunits and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
  Proteasomes are widely distributed in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
  A modified form, the immunoproteasome, processes class I MHC peptides.
  PSMD11 is a non-ATPase subunit of the 19S regulator.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.