Thermo Fisher Scientific TDRD3 Chimeric Recombinant Rabbit Monoclonal Antibody (RAB-C419)
TDRD3 단백질을 특이적으로 인식하는 재조합 토끼 단클론 항체. Western blot, ICC/IF, Flow cytometry 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도. 인간 시료 반응성, 비결합형 액상 포맷.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 0.1–1 µg/mL | |
| Immunocytochemistry (ICC/IF) | 1:100 | |
| Flow Cytometry (Flow) | 1:100 | |
| ELISA | Assay-dependent | |
| Immunoprecipitation (IP) | Assay-dependent | |
| ChIP assay (ChIP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | RAB-C419 |
| Immunogen | Recombinant antibody (rAb) phage display recognizing TDRD3 protein under non-denaturing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074782 |
Product Specific Information
Specificity:
This antibody recognizes TDRD3 (Tudor domain-containing protein 3). It binds to a folded domain (amino acids 1–455). TDRD3 is a scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins.
Target Information
TDRD3 belongs to the tudor domain group of proteins, which are prevalent among proteins involved in RNA metabolism. TDRD3 is widely expressed and localizes predominantly in the cytoplasm. It is detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Overexpression of TDRD3 in cells induces the formation of stress granules. Multiple isoforms of TDRD3 exist due to alternative splicing variants. In humans, the gene is located on chromosome 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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