Thermo Fisher Scientific Coilin Monoclonal Antibody (Pdelta)
Human Coilin 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Recombinant C-terminal fragment를 면역원으로 사용했으며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA125322
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–2 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Pdelta |
| Immunogen | Recombinant fragment corresponding to the 389 residue, C-terminal portion of human Coilin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.9 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2081426 |
Product Specific Information
- Recommended positive controls: HeLa nuclear extract
- MA1-25322 will not react with mouse
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs.
The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influence its localization among nuclear bodies and the composition and assembly of Cajal bodies.
This gene has pseudogenes on chromosome 4 and chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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