Thermo Fisher Scientific Human ZIP10 Synthetic Peptide
인간 ZIP10 단백질의 중심부 18개 아미노산 서열로 구성된 합성 펩타이드. ZIP10 항체의 블로킹 펩타이드로 사용 가능. 아연 수송 단백질 연구 및 관련 질환 연구에 활용. 액상 형태, PBS 완충액에 0.1% BSA 포함, -20°C 보관.
- 카탈로그번호
- PEP1178
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the center of human ZIP10.
PEP-1178 can be used as a blocking peptide with polyclonal antibody PA5-21064.
Target Information
ZIP10, also known as Slc39A10, is a widely expressed zinc transporter with nine transmembrane domains. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation.
ZIP10 mRNA was found to be significantly decreased in the intestines and kidneys of hypothyroid rats and increased in those of hyperthyroid rats, indicating positive regulation by thyroid hormones.
ZIP10 mRNA was also found to be upregulated in invasive and metastatic breast cancer and cell lines, suggesting that ZIP10 could serve as a possible marker for the metastatic phenotype and a potential target for novel treatment strategies.
At least three isoforms of ZIP10 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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