Thermo Fisher Scientific Human SLC39A4 Synthetic Peptide
인간 SLC39A4(ZIP4) 단백질의 중심부 15개 아미노산 서열 기반 합성 펩타이드입니다. ZIP4 관련 항체의 블로킹 펩타이드로 사용 가능하며, 정제된 액상 형태로 제공됩니다. PBS(pH 7.2) + 0.1% BSA 버퍼에 보관하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1183
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the center of human ZIP4.
PEP-1183 can be used as a blocking peptide with polyclonal antibody PA5-21069.
Target Information
The zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in growth, development, and differentiation. ZIP4 was initially identified as a zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in the absorption of dietary zinc.
Similar to other ZIP family members, aberrant expression of ZIP4 has been linked to cancer, specifically the progression and aggressiveness of pancreatic cancer. ZIP4 expression has also been shown to be activated in hepatocellular carcinomas, acting to repress apoptosis, enhance cell cycle, and increase migration, suggesting ZIP4 may play a role in multiple types of cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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