Thermo Fisher Scientific Fbx32 Monoclonal Antibody (2A3)
Fbx32 단백질을 인식하는 Rabbit Monoclonal Antibody(2A3)로, Western Blot 및 Immunocytochemistry에 적합. 비결합형 액상 형태이며, 1 mg/mL 농도로 제공. 근육 위축 관련 연구에 활용 가능. 연구용으로만 사용.
- 카탈로그번호
- BSM-54451R
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A3 |
| Immunogen | Recombinant human Fbx32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. F-box proteins are part of the ubiquitin protein ligase complex (SCF), which functions in phosphorylation-dependent ubiquitination. They are divided into three classes:
- Fbws: containing WD-40 domains
- Fbls: containing leucine-rich repeats
- Fbxs: containing other interaction modules or no recognizable motifs
The encoded protein belongs to the Fbxs class and contains an F-box domain. It is highly expressed during muscle atrophy, while deficiency in this gene confers resistance to atrophy in mice. This makes it a potential drug target for the treatment of muscle atrophy. Alternative splicing results in two transcript variants encoding isoforms of different sizes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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