Thermo Fisher Scientific RTCA Polyclonal Antibody
Human RTCA를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, PBS/glycerol buffer에 보존. 연구용으로 RNA 처리 관련 단백질 분석에 적합.
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Thermo Fisher Scientific RTCA Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RTCA. Recombinant protein control fragment (Product #RP-94250) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646857 |
Product Specific Information
- Immunogen sequence:
PLRVQKIRAG RSTPGLRPQH LSGLEMIRDL CDGQLEGAEI GSTEITFTPE KIKGGIHTAD TKTAGSVCLL MQVSMPCV - Highest antigen sequence identity to the following orthologs:
Mouse - 94%, Rat - 95%.
Target Information
RTCD1 catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The enzyme acts through three steps:
- Adenylation of the enzyme by ATP
- The enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A
- A non-catalytic nucleophilic attack by the adjacent 2'-hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product
The biological role of this enzyme is not fully known but it is likely involved in cellular RNA processing. Two isoforms are known.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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