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Thermo Fisher Scientific RTCA Polyclonal Antibody
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Thermo Fisher Scientific RTCA Polyclonal Antibody

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Human RTCA를 인식하는 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 제품이며, PBS/glycerol buffer에 보존. 연구용으로 RNA 처리 관련 단백질 분석에 적합.

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마지막 업데이트 2025. 07. 29. 오후 02:38
Thermo Fisher Scientific PA555777 RTCA Polyclonal Antibody 100 ul pk판매 단위 pk ·
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773,300원VAT 포함 850,630원

Thermo Fisher Scientific · Thermo Fisher Scientific RTCA Polyclonal Antibody

Thermo Fisher Scientific RTCA Polyclonal Antibody

Applications

  • Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Recombinant protein corresponding to Human RTCA. Recombinant protein control fragment (Product #RP-94250)
Conjugate Unconjugated
Form Liquid
Concentration 0.1 mg/mL
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions Wet ice
RRID AB_2646857

Product Specific Information

  • Immunogen sequence:
    PLRVQKIRAG RSTPGLRPQH LSGLEMIRDL CDGQLEGAEI GSTEITFTPE KIKGGIHTAD TKTAGSVCLL MQVSMPCV
  • Highest antigen sequence identity to the following orthologs:
    Mouse - 94%, Rat - 95%.

Target Information

RTCD1 catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The enzyme acts through three steps:

  1. Adenylation of the enzyme by ATP
  2. The enzyme acts on RNA-N3'P to produce RNA-N3'PP5'A
  3. A non-catalytic nucleophilic attack by the adjacent 2'-hydroxyl on the phosphorus in the diester linkage to produce the cyclic end product

The biological role of this enzyme is not fully known but it is likely involved in cellular RNA processing. Two isoforms are known.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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