Thermo Fisher Scientific DYNLL1 Polyclonal Antibody
DYNLL1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot에 적합. Human, Mouse, Rat에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 안정적. 연구용으로 적합.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DYNLL1 (Accession P63167), corresponding to amino acid residues M1–D47 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2850393 |
Product Specific Information
Antibody detects endogenous levels of total DYNLL1.
Target Information
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains and stalks linking the heads to a basal domain that includes accessory intermediate chains. The complex is involved in intracellular transport and motility.
DYNLL1 is a light chain component of this complex and physically interacts with neuronal nitric oxide synthase (nNOS), inhibiting its activity. Binding of DYNLL1 destabilizes the nNOS dimer, which is necessary for enzymatic activity, thereby regulating multiple biological processes through modulation of nitric oxide synthase activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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