Thermo Fisher Scientific PIK3C2B Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total PIK3C2B.

Target Information

The Class II PI3 kinases, including PIK3C2B, phosphorylate the 3 position of PI or PI4P. Though not as well studied as the class I PI3 kinases, the class II enzymes have been linked to diverse receptor-mediated cellular processes including insulin signaling, neuronal survival, and growth factor signaling.
Protein kinases are enzymes that transfer a phosphate group from ATP onto an acceptor amino acid in a substrate protein, mediating signal transduction and regulating metabolism, transcription, cell cycle, cytoskeletal rearrangement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest in eukaryotes and is classified into 8 major groups based on sequence comparison of their catalytic domains.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.