Thermo Fisher Scientific Desmocollin 2 Polyclonal Antibody
Human DSC2 단백질을 인식하는 Rabbit Polyclonal Antibody. IHC(P) 및 ELISA에 사용 가능. 보존제 무첨가로 고순도 정제됨. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용.
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Thermo Fisher Scientific Desmocollin 2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human DSC2 protein (Met1–Arg684) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787862 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
This antibody has specificity for Human DSC2.
Target Information
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome.
Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress.
This gene is located in a cluster with other desmocollin family members on chromosome 18.
Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer.
Alternative splicing results in multiple transcript variants.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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