Thermo Fisher Scientific EDG3 Polyclonal Antibody
Human EDG3/S1P3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 연구용으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며 PBS buffer에 0.1% sodium azide 포함. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 4–20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from C-terminus of human EDG3 / S1P3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550874 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Monkey (100%)
- Marmoset, Elephant (94%)
- Bovine (89%)
- Gibbon, Rabbit (83%)
Target Information
EDG-3 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-3 is sphingosine-1-phosphate. There are eight known members of the EDG receptor family, which mediate growth-related effects such as cellular proliferation, differentiation, survival, and suppression of apoptosis. They also evoke cytoskeletal-dependent cellular responses including contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated, differ in tissue distribution, and couple to multiple G proteins to signal through ras and MAP kinase, rho, phospholipase C, and various protein tyrosine kinases. EDG-3 is expressed in cardiovascular, leukocyte-containing, and other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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