Thermo Fisher Scientific GPR18 Polyclonal Antibody
GPR18 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 항원 친화 크로마토그래피로 정제되었으며 1 mg/mL 농도, PBS 버퍼 및 0.02% sodium azide 함유. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | View 2 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | View publications |
| Immunocytochemistry (ICC/IF) | 2–10 µg/mL | View publications |
| Flow Cytometry (Flow) | Assay-Dependent | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Partial synthetic peptide made to an N-terminal portion of the human GPR18 protein (amino acids 1–50) [UniProt Q14330] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2540743 |
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600–1,000 members and represents the largest known class of molecular targets with therapeutic potential.
GPR18 is an orphan G protein-coupled receptor expressed at high levels in the testis, small intestines, and immune-related cells such as lymphocytes, thymus, and spleen.
It acts as a receptor for endogenous lipid neurotransmitters, some of which also bind cannabinoid receptors.
Known agonists or partial agonists include:
- N-Arachidonoylglycine
- Abnormal cannabidiol
- O-1602
- AM-251
- Cannabidiol
- Δ9-Tetrahydrocannabinol
- N-arachidonoyl ethanolamine
- Arachidonylcyclopropylamide
Known antagonists include:
- CID-85469571
- O-1918
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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