Thermo Fisher Scientific Human TIMP1 Recombinant Protein
인간 TIMP1 재조합 단백질로 다양한 면역학적 분석의 양성 대조군으로 사용 가능. E. coli 발현 시스템을 통해 생산된 고순도(>95%) His-tag 단백질. 세포 성장, 이동, 사멸 조절 연구에 적합. -20°C에서 보관, 동결/해동 반복 피해야 함.
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Thermo Fisher Scientific Human TIMP1 Recombinant Protein
Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Cys24–Ala207 containing an N-terminal His-tag |
| Tag | His-tag |
| Molecular Weight | 25.21 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.29 mg/mL |
| Purification | Purified |
| Storage Buffer | 25 mM sodium acetate, pH 4.8, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains a purified 184 amino acid fragment (aa24–207) corresponding to the mature TIMP-1 protein with an N-terminal hexahistidine tag.
It may be used as a positive control in many immunological assays.
Target Information
TIMP1 (metalloproteinase inhibitor 1) is a metalloproteinase inhibitor that forms one-to-one complexes with target metalloproteinases such as collagenases and inactivates them by binding to their catalytic zinc cofactor.
It acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP14, and MMP16.
Additionally, TIMP1 functions as a growth factor regulating cell differentiation, migration, and apoptosis.
It activates cellular signaling cascades via CD63 and ITGB1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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