Thermo Fisher Scientific FAM3B Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 FAM3B 단백질(aa 30-235)을 인식합니다. Western blot에 1:500–1:2,000 희석 비율로 사용 가능합니다. 액상 형태, 1.5 mg/mL 농도이며 -20°C 보관. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 30–235 of human FAM3B (NP_478066.3) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2913828 |
Product Specific Information
- Positive test controls: Mouse intestine
- Localization: Secreted
- Immunogen sequence:
ELIPDAPLSS AAYSIRSIGE RPVLKAPVPK RQKCDHWTPC PSDTYAYRLL SGGGRSKYAK ICFEDNLLMG EQLGNVARGI NIAIVNYVTG NVTATRCFDM YEGDNSGPMT KFIQSAAPKS LLFMVTYDDG STRLNNDAKN AIEALGSKEI RNMKFRSSWV FIAAKGLELP SEIQREKINH SDAKNNRYSG WPAEIQIEGC IPKERS
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine. FAM3B functions as an islet-specific cytokine promoting apoptosis and may inhibit insulin secretion from beta-cells, possibly influencing pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse homolog, indicating a conserved role. Three isoforms (A, B, and C) exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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