Thermo Fisher Scientific NAPSA Monoclonal Antibody (10C4B8)
NAPSA 단백질을 인식하는 Mouse monoclonal antibody (Clone 10C4B8). Western blot, IHC, Flow cytometry, ELISA에 사용 가능. Human 및 Rat 시료 반응성. Protein G 정제, PBS buffer, 1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10C4B8 |
| Immunogen | Purified recombinant fragment of human NAPSA (AA: 20–158) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3090533 |
Target Information
Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. It processes surfactant protein B in healthy pulmonary and renal tissues but is abnormally regulated during carcinogenesis. Napsin evaluation is useful in identifying several cancers and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, it serves as a specific biomarker for carcinoma differentiation. Napsin has also been associated with pulmonary alveolar proteinosis and protein catabolism in renal tubules.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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