Thermo Fisher Scientific EDG4 Polyclonal Antibody
EDG4 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, IHC 및 ICC/IF에 적합합니다. 인간, 마우스, 랫트 반응성이 있으며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA575339
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 298–343 of Human EDG4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719067 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Edg4 is a Lysophospholipid/Lysosphingolipid receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes.
In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion.
Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. It has also been observed in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid.
ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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