Thermo Fisher Scientific NMNAT3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human NMNAT3. Validated for IHC (Paraffin) with dilution 1:1,000–1:2,500. Recombinant protein immunogen; affinity purified; stored in PBS with glycerol. For research use only.
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Thermo Fisher Scientific NMNAT3 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NMNAT3. Recombinant protein control fragment (Product #RP-96415). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644719 |
Product Specific Information
Immunogen sequence:
VDPWESEQAQ WMETVKVLRH HHSKLLRSPP QMEGPDHGKA LFSTPAAVPE LKLLCGADVL KTFQTPNLWK DAHIQEIVEK FGLVCV
Highest antigen sequence identity to the following orthologs:
- Mouse: 84%
- Rat: 83%
Target Information
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form, nicotinic acid mononucleotide (NaMN), with similar efficiency. Can use triazofurin monophosphate (TrMP), GTP, and ITP as substrates.
Also catalyzes the reverse reaction (pyrophosphorolytic cleavage of NAD(+)). For this activity, can use NAD(+), NADH, NAAD, NHD, and NGD as substrates, but not NADP(+), NADPH, or NAADP(+).
Protects against axonal degeneration following injury.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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