Thermo Fisher Scientific TRDMT1 Monoclonal Antibody (OTI8H10), TrueMAB

Thermo Fisher Scientific TRDMT1 Monoclonal Antibody (OTI8H10), TrueMAB

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:2,000

Species Reactivity

• Human
• Mouse

Host / Isotype

• Mouse / IgG1

Class

• Monoclonal

Type

• Antibody

Clone

• OTI8H10

Immunogen

Human recombinant protein fragment corresponding to amino acids 84–293 of human TRDMT1 produced in E. coli.

Conjugate

• Unconjugated

Form

• Lyophilized

Concentration

• 1 mg/mL

Purification

• Affinity chromatography

Storage Buffer

• PBS, pH 7.3, with 8% trehalose

Contains

• No preservative

Storage Conditions

• –20°C, Avoid Freeze/Thaw Cycles

Shipping Conditions

• Ambient (domestic)
• Wet ice (international)

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

CpG methylation is an epigenetic modification essential for embryonic development, imprinting, and X-chromosome inactivation.
Studies in mice show DNA methylation is required for mammalian development.
This gene encodes a protein similar to DNA methyltransferases but lacking methyltransferase activity.
The protein binds DNA strongly, suggesting a role in marking specific genomic sequences.
Alternative splicing yields multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.