Thermo Fisher Scientific IGF2BP3 Monoclonal Antibody (OTI5G10), TrueMAB
IGF2BP3 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. Human, Mouse, Rat 시료에 반응하며, 무보존제 PBS 완충액에 동결건조 형태로 제공. 재용해 후 1 mg/mL 농도로 사용 가능. 연구용으로 암 관련 단백질 발현 분석에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G10 |
| Immunogen | Full length human recombinant protein of human IGF2BP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended.
(Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882)
Target Information
Insulin-like growth factor-II mRNA-binding protein 3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the IGF-II mRNA-binding protein family.
IMP-3 is expressed during embryogenesis and in certain malignancies. It is present in malignant melanoma but not in benign nevi, even with dysplastic features. IMP-3 expression is significantly higher in melanomas than in Spitz nevi, and more abundant in metastatic melanomas compared to thin melanomas.
It may play an important role in tumor progression and regulation of malignant behavior.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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