Thermo Fisher Scientific CD177 Polyclonal Antibody, MaxPab
CD177 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, 인간 시료에 반응합니다. Western blot에 최적화되어 있으며, PBS 기반 액상 형태로 제공됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
- 카탈로그번호
- H00057126-D01P
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | CD177 (AAH29167.1, 1 a.a. ~ 437 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of CD177 protein:
MSPVLLLALL GFILPLPGVQ ALLCQFGTVQ HVWKVSDLPR QWTPKNTSCD SGLGCQDTLM LIESGPQVSL VLSKGCTEAK DQEPRVTEHR MGPGLSLISY TFVCRQEDFC NNLVNSLPLW APQPPADPGS LRCPVCLSME GCLEGTTEEI CPKGTTHCYD GLLRLRGGGI FSNLRVQGCM PQPGCNLLNG TQEIGPVGMT ENCNRKDFLT CHRGTTIMTH GNLAQEPTDW TTSNTEMCEV GQVCQETLLL LDVGLTSTLV GTKGCSTVGA QNSQKTTIHS APPGVLVASY THFCSSDLCN SASSSSVLLN SLPPQAAPVP GDRQCPTCVQ PLGTCSSGSP RMTCPRGTTH CYDGYIHLSG GGLSTKMSIQ GCVAQPSSFL LNHTRQIGIF SAREKRDVQP PASQHEGGGA EGLESLTWGV GLALAPALWW GVVCPSC
Target Information
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein mainly expressed on neutrophils. Its membrane expression increases during pregnancy, inflammation, or after G-CSF treatment. CD177 interacts with CD31 (PECAM-1) and plays a role in neutrophil transmigration and proliferation. Antibodies against CD177 may be associated with neonatal alloimmune neutropenia (NAN).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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