Thermo Fisher Scientific H2AFY2 Monoclonal Antibody (OTI1E1), TrueMAB
인간 H2AFY2 단백질을 인식하는 마우스 모노클로날 항체로 Western blot 및 IHC(P) 적용 가능. 고순도 친화 크로마토그래피 정제, 무보존제 PBS 버퍼에 동결건조 형태로 제공. 연구용으로 전사 억제 및 염색체 안정성 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–261 of human H2AFY2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Variant histone H2A that replaces conventional H2A in a subset of nucleosomes where it represses transcription.
Histones play a central role in transcription regulation, DNA repair, replication, and chromosomal stability.
DNA accessibility is modulated by post-translational modifications (histone code) and nucleosome remodeling.
H2AFY2 may contribute to stable X chromosome inactivation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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