Thermo Fisher Scientific Noggin Polyclonal Antibody
Human 및 Mouse에서 반응하는 Noggin 단백질 검출용 폴리클로날 항체. Western blot과 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 Liquid 형태, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 0.2–1 µL/mg of lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the N-terminus of the human NOG |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2866790 |
Product Specific Information
This antibody reacts with Human and Mouse (species predicted to react based on 100% sequence homology).
Target Information
Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. Organ morphogenesis is initiated by downgrowth from epithelial stem cells, regulated by WNT3A (stabilizing beta-catenin) and Noggin, a bone morphogenetic protein inhibitor.
Mutations in Noggin are associated with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1), characterized by multiple joint fusions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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