Thermo Fisher Scientific CACNB1 Polyclonal Antibody
Rabbit polyclonal antibody targeting CACNB1, reactive with human, mouse, and rat. Suitable for WB and IHC applications. Lyophilized form with PBS buffer, no preservative. High specificity and cross-species identity for calcium channel research.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 10–50 µg/mL | – |
| Immunohistochemistry (IHC) | 10–50 µg/mL | – |
| Miscellaneous (PubMed) | – | View 1 publication |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from the N-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein. The antigen shares 98% identity with rat and human sequences. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: CACNB1.
Target Information
Calcium Channel 1 is a protein encoded by the CACNB1 gene and belongs to the calcium channel beta subunit family.
It plays an important role in calcium channel function by:
- Modulating G protein inhibition
- Increasing peak calcium current
- Controlling alpha-1 subunit membrane targeting
- Shifting voltage dependence of activation and inactivation
Dysfunction of this protein is associated with malignant hyperthermia susceptibility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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