Thermo Fisher Scientific Phospho-EEF2K (Ser366) Polyclonal Antibody
인간, 비인간 영장류, 랫트 반응성을 가진 Rabbit Polyclonal 항체로, Ser366 인산화된 eEF2K를 인식합니다. Western Blot 및 Immunoprecipitation에 사용 가능하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PA517719
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunoprecipitation (IP)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer366 of human eEF2K |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10977545 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
EEF2K is a highly conserved serine/threonine kinase in the calmodulin signaling pathway. Its activity is increased in cancers, including breast cancer. EEF2K regulates protein synthesis by controlling peptide chain elongation. Upon activation by upstream kinases such as AMPK or TRPM7, EEF2K phosphorylates elongation factor EEF2 at a single site, rendering EEF2 unable to bind ribosomes and thereby reducing the rate of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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