Thermo Fisher Scientific EEF2K Polyclonal Antibody
EEF2K 단백질 인산화 조절 연구용 Rabbit Polyclonal 항체. Western blot, ICC/IF, IP에 적합하며 Human, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, 보존제 없이 -20°C에서 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Immunoprecipitation (IP) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding the N-terminus of human eEF2K |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981348 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
EEF2K (eukaryotic elongation factor 2 kinase) is a highly conserved serine/threonine kinase in the calmodulin signaling pathway. Its activity is increased in several cancers, including breast cancer. EEF2K regulates protein synthesis by controlling peptide chain elongation. Upon activation by upstream kinases such as AMPK or TRPM7, EEF2K phosphorylates elongation factor EEF2 at a single site, preventing EEF2 from binding ribosomes and thereby reducing the rate of protein synthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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