Thermo Fisher Scientific SMC2 Polyclonal Antibody
SMC2 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(P) 실험에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol buffer로 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMC2 (Accession O95347), corresponding to amino acid residues K930–G980 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900564 |
Product Specific Information
Antibody detects endogenous levels of total SMC2.
Target Information
CAP-E and CAP-C (Chromosome Associated Protein-E & C) are members of the SMC (Structural Maintenance of Chromosome) family that form a heterodimeric complex required for mitotic chromosome condensation, ensuring proper segregation of genetic information during cell division.
The hCAP-C/hCAP-E complex, a component of the condensin multiprotein complex, interacts with phosphorylated Histone H3 to mediate mitotic chromosome condensation.
Distribution patterns of the two heterodimeric complexes in the interphase nucleus indicate independent behavior during the cell cycle, suggesting that these complexes are involved in distinct aspects of mitotic chromosome organization in human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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