Thermo Fisher Scientific RING1 Monoclonal Antibody (OTI6F11), TrueMAB
RING1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 인간 유래 단백질 조각(aa 88-362)을 면역원으로 사용하였으며, 액상 형태로 제공됩니다. 1 mg/mL 농도, PBS/BSA/glycerol 완충액에 보관되며 -20°C에서 안정적으로 저장 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 88–362 of human RING1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The RING1 gene belongs to the RING finger family, which encodes proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex and interacts with proteins such as BMI1, EDR1, and CBX4, colocalizing with them in large nuclear domains. The CBX4 interaction occurs via the glycine-rich C-terminal domain. The gene maps to the HLA class II region, adjacent to the RING finger genes FABGL and HKE4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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