Thermo Fisher Scientific PATZ1 Monoclonal Antibody (OTI2H4), TrueMAB
PATZ1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot에 적합합니다. 인간 유래 단백질을 면역원으로 제작되었으며, 고순도의 액상 형태로 제공됩니다. Affinity chromatography로 정제되었고, 안정적인 PBS/BSA/glycerol 버퍼에 보관됩니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2H4 |
| Immunogen | Full length human recombinant protein of human PATZ1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PATZ1 protein contains an A-T hook DNA-binding motif that interacts with other DNA-binding structures and plays a crucial role in chromatin modeling and transcription regulation.
Its POZ domain mediates protein–protein interactions required for transcriptional repression, while zinc-finger domains constitute the DNA-binding region.
PATZ1 acts as a transcriptional repressor and can form fusion proteins with EWS in small round cell sarcoma due to chromosomal rearrangements involving 22q.
Multiple alternatively spliced transcript variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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