Thermo Fisher Scientific IL1R2 Recombinant Rabbit Monoclonal Antibody (016)

Applications

• ELISA (ELISA): 1:5,000–1:10,000

Product Specifications

Product Specific Information

This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.

Advantages of recombinant rabbit monoclonal antibodies:

• High specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity due to larger rabbit immune repertoire

This antibody has specificity for Mouse IL-1R2/CD121b.

Target Information

The IL1R2 gene encodes a cytokine receptor belonging to the interleukin 1 receptor family. This protein binds IL1A, IL1B, and IL1R1/IL1RA, acting as a decoy receptor that inhibits ligand activity. IL4 can antagonize IL1 activity by inducing IL1R2 expression and release. The gene forms part of a cytokine receptor cluster on chromosome 2q12, with two alternatively spliced transcript variants encoding the same protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.