Thermo Fisher Scientific ATF1 Polyclonal Antibody
Rabbit에서 유래한 ATF1 폴리클로날 항체로 Western blot에 적합합니다. 인간 단백질에 반응하며, C-말단 합성 펩타이드를 면역원으로 사용했습니다. 액상 형태로 0.5 mg/mL 농도이며, PBS와 sucrose buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human ATF1 (aa 222–271) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609279 |
Product Specific Information
Peptide sequence:
KNREAARECR RKKKEYVKCL ENRVAVLENQ NKTLIEELKT LKDLYSNKSV
Sequence homology:
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%; Sheep: 77%; Zebrafish: 100%
Target Information
This gene encodes an activating transcription factor belonging to the ATF subfamily and bZIP (basic-region leucine zipper) family. It regulates downstream genes associated with growth, survival, and cellular activities. The protein is phosphorylated at serine 63 by several kinases including PKA, CaMK I/II, MSK, and CDK3, which enhances transactivation and cell transformation. Gene fusions with FUS (chromosome 16) or EWSR1 (chromosome 22) produce chimeric proteins implicated in angiomatoid fibrous histiocytoma and clear cell sarcoma. A pseudogene exists on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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