Thermo Fisher Scientific ETV1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000
• Publications: View 4 publications

Immunohistochemistry (IHC)

• Tested Dilution: 5 µg/mL
• Publications: View 2 publications

Product Specifications

Product Specific Information

• Peptide sequence:
  PDNQRPLLKT DMERHINEED TVPLSHFDES MAYMPEGGCC NPHPYNEGYV

• Sequence homology:
  Cow: 100%
  Dog: 100%
  Guinea Pig: 100%
  Horse: 100%
  Human: 100%
  Mouse: 100%
  Rabbit: 86%
  Rat: 100%
  Zebrafish: 86%

Target Information

ETV1 (ets variant gene 1)
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins share the same central core sequence but interact with unique flanking sequences. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 displays unique expression patterns suggesting its role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits it.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.