Thermo Fisher Scientific ETV1 Polyclonal Antibody
ETV1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot 및 IHC에 적합하며, 인간 종에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- Publications: View 4 publications
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
- Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human ETV1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608631 |
Product Specific Information
Peptide sequence:
PDNQRPLLKT DMERHINEED TVPLSHFDES MAYMPEGGCC NPHPYNEGYVSequence homology:
Cow: 100%
Dog: 100%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 100%
Rabbit: 86%
Rat: 100%
Zebrafish: 86%
Target Information
ETV1 (ets variant gene 1)
Several members of the Ets gene family encode sequence-specific DNA binding proteins that recognize DNA sequences with a centrally located 5'-GGAA-3' element. All Ets proteins share the same central core sequence but interact with unique flanking sequences. ER81 (also designated ETV1) binds the motif 5'-CGGAA/T-3'. ER81 is highly expressed in brain, testis, lung, and heart, and moderately expressed in spleen, pancreas, colon, and small intestine. During development, ER81 displays unique expression patterns suggesting its role in organogenesis. ERK-1 activates ER81 transcriptional activity while MAPKAP kinase 2 inhibits it.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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